堀 泰智 循環器科担当

氏名 堀 泰智(ほり やすとも)
学位・資格 獣医師
日本獣医循環器学会認定医
担当 循環器科
経歴 2001年　北里大学獣医畜産学部獣医学科卒業
2001年　小儀動物病院 勤務
2005年　北里大学獣医畜産学部小動物第3内科 助手
2007年　北里大学獣医畜産学部小動物第3内科 助教
2009年　北里大学獣医畜産学部博士(獣医学)取得
2010年　北里大学獣医学部小動物第2内科 講師
2015年　北里大学獣医学部小動物第2内科 准教授
2016年　酪農学園大学伴侶動物内科学IIユニット准教授・循環器科診療科長
2020年　大塚駅前どうぶつ病院　院長
業績 1. Adachi, M,. Igarashi, H,. Okamoto, M,. Tamamoto, T,. Hori, Y.: Large granular lymphocyte lymphoma in the skin and urinary bladder of a dog. J Vet Med Sci. 84:296-301, 2022.

2. Ogawa, M,. Hori, Y,. Kanno, N,. Iwasa, N,. Toyofuku, T,. Isayama, N,. Yoshikawa, A,. Akabane, R,. Sakatani, A,. Miyakawa, H,. Hsu, HH,. Miyagawa, Y,. Takemura, N.: Comparison of N-terminal pro-atrial natriuretic peptide and three cardiac biomarkers for discriminatory ability of clinical stage in dogs with myxomatous mitral valve disease. J Vet Med Sci.83:705-715, 2021.

3. Hori, Y,. Yamashita, Y,. Sakakibara, K,. Sano, T,. Hori, A.: Usefulness of pericardial lung ultrasonography for the diagnosis of cardiogenic pulmonary edema in dogs. Am J Vet Res. 81:227-232, 2020.

4. Hori, Y,. Fujimoto, E,. Nishikawa, Y,. Nakamura, T.: Left ventricular outflow tract pressure gradient changes after carvedilol-disopyramide cotherapy in a cat with hypertrophic obstructive cardiomyopathy. J Vet Cardiol. 29:40-46, 2020.

5. Hori, Y,. Iguchi, M,. Hirakawa, A,. Kamiya, Z,. Yamano, S,. Ibaragi, T,. Isayama, N,. Yamashita, Y,. Iwasa, N,. Inaba, H,. Heishima, Y,. Yuki, M.: Evaluation of atrial natriuretic peptide and cardiac troponin I concentrations for assessment of disease severity in dogs with naturally occurring mitral valve disease. J Am Vet Med Assoc. 256:340-348,2020.

6. Hori ,Y,. Iguchi, M., Hirakawa, A., Kamiya, Z., Yamano, S., Ibaragi, T., Isayama, N., Yamashita, Y., Iwasa, N., Inaba, H., Heishima, Y., Yuki, M.: Cardiac troponin I and atrial natriuretic peptide levels in dogs with spontaneous mitral valve disease. J Am Vet Med Assoc.

7. Hori, Y., Yamashita, Y., Sakakibara, K., Sano, T., Hori, A.: Usefulness of pericardial lung ultrasonography for the diagnosis of cardiogenic pulmonary edema in dogs. Am J Vet Res 81: 227-232, 2020.

8. Hori, Y., Taira, H., Nakajima, Y., Ishikawa, Y., Yumoto, Y., Maekawa, Y., Oshiro, A.: Inotropic effects of a single intravenous recommended dose of pimobendan in healthy dogs. J Vet Med Sci. 81: 22-25, 2019.

9. 4. Hori, Y., Heishima, Y., Yamashita, Y., Iguchi, M., Nakamura, K., Isayama, N., Onodera, H., Kitade, A., Kanno, N., Hirakawa, A., Katagi, M., Ibaragi, T., Yamano, S., Aramaki, Y., Sawada, T.: Epidemiological study of indirect blood pressure in clinically healthy cats measured using oscillometry at the initial evaluation. J Vet Med Sci. 81: 513-516, 2019.

10. Hori, Y., Nakamura, K., Kanno, N., Hitomi, M., Yamashita, Y., Hosaka, S., Isayama, N., Mimura, T.: Effects of the angiotensin-converting enzyme inhibitor alacepril in dogs with mitral valve disease. J Vet Med Sci. 80: 1212-1218, 2018.

11. Heishima, Y., Hori, Y., Nakamura, K., Yamashita, Y., Isayama, N., Kanno, N., Katagi, M., Onodera, H., Yamano, S., Aramaki, Y.: Diagnostic accuracy of plasma atrial natriuretic peptide concentrations in cats with and without cardiomyopathies. J Vet Cardiol. 20: 234-243, 2018.

12. Hori, Y., Iguchi, M., Heishima, Y., Yamashita, Y., Nakamura, K., Hirakawa, A., Kitade, A., Ibaragi, T., Katagi, M., Sawada, T., Yuki, M., Kanno, N., Inaba, H., Isayama, N., Onodera, H., Iwasa, N., Kino, M., Narukawa, M., Uchida, S.: Diagnostic utility of cardiac troponin I in cats with hypertrophic cardiomyopathy. J Vet Int Med. 32: 922-929, 2018.

13. Hori, Y., Heishima, Y., Yamashita, Y., Isayama, N., Kanno, N., Nakamura, K., Iguchi, M., Ibaragi, T., Onodera, H., Aramaki, Y., Hirakawa, A., Yamano, S., Katagi, M., Kitade, A., Sawada, T.: Relationship between indirect blood pressure and various stages of chronic kidney disease in cats. J Vet Med Sci. 80: 447-452, 2018.

14. Hori, Y., Touei, D., Saitoh, R., Yamagishi, M., Kanai, K., Hoshi, F., Itoh, N.: The Aldosterone Receptor Antagonist Eplerenone Inhibits Isoproterenol-induced Collagen-I and 11β-HSD1 Expression in Rat Cardiac Fibroblasts and the Left Ventricle. Biol. Pharm. Bull. 40: 1716-1723, 2017.

15. Heishima, Y., Hori, Y., Chikazawa, S., Kanai, K., Hoshi, F., Itoh, N.: Indirect arterial blood pressure measurement in healthy anesthetized cats using a device that combines oscillometry with photoplethysmography. J Vet Med Sci. 78: 1179-1182, 2016.

16. Kanno, N., Hori, Y., Hidaka, Y., Chikazawa, S., Knai, K., Hoshi, F., Itoh, N.: Plasma atrial natriuretic peptide and N-terminal pro B-type natriuretic peptide concentrations in dogs with right-sided congestive heart failure. J Vet Med Sci. 78: 535-542, 2016.

17. Heishima, Y., Hori, Y., Chikazawa, S., Kanai, K., Hoshi, F., Itoh, N.: Influence of storage conditions on in vitro stability of atrial natriuretic peptide and of anesthesia on plasma atrial natriuretic peptide concentration in cats. Am J Vet Res. 77: 854-859, 2016.

18. Hori, Y., Kondo, C., Matsui, M., Yamagishi, M., Okano, S., Chikazawa, S., Kanai, K., Hoshi, F., Itoh, N.: Effect of the phosphodiesterase type 5 inhibitor tadalafil on pulmonary hemodynamics in healthy dogs. Vet J. 202: 334-339, 2014.

19. Itoh, N., Oohashi, Y., Ichikawa-Seki, M., Itagaki, T., Ito, Y., Saeki, H., Kanai, K., Chikazawa, S., Hori, Y., Hoshi, F., Higuchi, S.: Molecular detection and characterization of Cryptosporidium species in household dogs, pet shop puppies, and dogs kept in a school of veterinary nursing in Japan. Vet Parasitol. 200: 284-288, 2014.

20. Kobayashi, K., Hori, Y., Chimura, S.: Plasma N-terminal pro B-type Natriuretic Peptide Concentrations in Dogs with Pulmonic Stenosis. J Vet Med Sci. 76: 827-831, 2014.

21. Itoh, N., Ito, Y., Kato, A., Kanai, K., Chikazawa, S., Hori, Y., Hoshi, F., Higuchi, S.: Prevalence of intestinal parasites in pet shop kittens in Japan. J Feline Med Surg. 15: 908-910, 2013.

22. Chikazawa, S., Kitahara, Y., Ando, E., Hori, Y., Hoshi, F., Kanai, K., Ito, N., Higuchi, S.: Erythrophagocytosis Enhances Heme-Dependent Cytotoxicity of Antimalarial Drugs in Canine Histiocytic Sarcoma Cell Line DH82. J Vet Med Sci. 76: 249-253, 2013.

23. Chikazawa, S., Hori, Y., Kanai, K., Ito, N., Hoshi, F., Orino, K., Watanabe, K., Higuchi, S.: Factors Influencing Measurement of Serum Iron Concentration in Dogs: Diurnal Variation and Hyperferritinemia. J Vet Med Sci. 75: 1615-1618, 2013.

24. Chikazawa, S., Nakazawa, T., Hori, Y., Hoshi, F., Kanai, K., Ito, N., Orino, K., Watanabe, K., Higuchi, S.: Change in Serum Ferritin Concentration in Experimentally Induced Anemia of Chronic Inflammation in Dogs. J Vet Med Sci. 75: 1419-1426, 2013.

25. Chikazawa, S., Hori, Y., Hoshi, F., Kanai, K., Ito, N., Higuchi, S.: Hyperferritinemia in Dogs with Splenic Hemangiosarcoma. J Vet Med Sci. 75: 1515-1518, 2013.

26. Chikazawa, S., Hori, Y., Hoshi, F., Kanai, K., Ito, N., Sato, J., Orino, K., Watanabe, K., Higuchi, S.: Development of a sandwich enzyme-linked immunosorbent assay to detect and measure serum levels of canine ferritin. J Vet Med Sci. 75: 515-517, 2013.

27. Hori, Y., Kashimoto, T., Yonezawa, T., Sano, N., Saitoh, R., Igarashi, S., Chikazawa, S., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Matrix metalloproteinase-2 stimulates collagen-I expression through phosphorylation of focal adhesion kinase in rat cardiac fibroblasts. Am J Physiol Cell Physiol. 303: C947-53, 2012.

28. Hori, Y., Uchide, T., Saitoh, R., Thoei, D., Uchida, D., Chikazawa, S., Hoshi, F.: Diagnostic utility of NT-proBNP and ANP in a canine model of chronic embolic pulmonary hypertension. Vet J. 194: 215-221, 2012.

29. Hori, Y., Ohshima, N., Chikazawa, S., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Myocardial injury-related changes in plasma NT-proBNP and ANP concentrations in a canine model of ischemic myocardial injury. Vet J. 191: 46-51, 2012.

30. Itoh, N., Ikegami, H., Takagi, M., Ito, Y., Kanai, K., Chikazawa, S., Hori, Y., Hoshi, F., Higuchi, S.: Prevalence of intestinal parasites in private-household cats in Japan. J Feline Med Surg.; 14: 436-439, 2012.

31. Kanai, K., Ito, Y., Nagai, N., Itoh, N., Hori, Y., Chikazawa, S., Hoshi, F., Higuchi, S.: Effects of instillation of eyedrops containing disulfiram and hydroxypropyl-β-cyclodextrin inclusion complex on endotoxin-induced uveitis in rats. Curr Eye Res.37: 124-131, 2012

32. Yamano, S., Uechi, M., Tanaka, K., Hori, Y., Ebisawa, T., Harada, K., Mizukoshi, T.: Surgical repair of a complete endocardial cushion defect in a dog. Vet Surg. 40: 408-412, 2011.

33. Fukumoto, S., Hanazono, K., Kawasaki, N., Hori, Y., Higuchi, S., Sasaki, T., Temma, K., Uchide, T.: Anaplastic Atypical Myeloma with Extensive Cutaneous Involvement in a Dog. J Vet Med Sci. 74: 111-115, 2011.

34. Itoh, N., Itagaki, T., Kawabata, T., Konaka, T., Muraoka, N., Saeki, H., Kanai, K., Chikazawa, S., Hori, Y., Hoshi, F., Higuchi, S.: Prevalence of intestinal parasites and genotyping of Giardia intestinalis in pet shop puppies in east Japan. Vet Parasitol. 176: 74-78, 2011.

35. Itoh, N., Kanai, K., Tominaga, H., Kawamata, J., Kaneshima, T., Chikazawa, S., Hori, Y., Hoshi, F., Higuchi, S.: Giardia and other intestinal parasites in dogs from veterinary clinics in Japan. Parasitol Res. 109: 253-256, 2011.

36. Aramaki, Y., Chimura, S., Hori, Y., Eguchi, T.: Therapeutic changes of plasma N-terminal pro-brain natriuretic peptide concentrations in 9 dogs with patent ductus arteriosus. J Vet Med Sci. 73: 83-88, 2011.

37. Hori, Y., Yamano, S., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Clinical implications of plasma atrial natriuretic peptide levels in dogs with spontaneous heart disease. J Am Vet Med Assoc. 239: 1077-1083, 2011.

38. Nakata, J., Nakahari, A., Kato, Y., Yamachi, N., Sato, N., Yonezawa, T., Takahashi, C., Chikazawa, S., Hori, Y., Kanai, K., Ito, N., Higuchi, S., Hoshi, F.: Molecular cloning and expression analysis of feline alpha(1)-microglobulin. Vet Immunol Immunopathol. 139: 79-82, 2011.

39. Kanai, K., Itoh, N., Ito, Y., Nagai, N., Hori, Y., Chikazawa, S., Hoshi, F., Higuchi, S.: Anti-Inflammatory Potency of Oral Disulfiram Compared with Dexamethasone on Endotoxin-Induced Uveitis in Rats. J Vet Med Sci. 73: 517-520, 2011.

40. Hori, Y., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Spironolactone decreases isoproterenol-induced ventricular fibrosis and matrix metalloproteinase-2 in rats. Biol Pharm Bull. 34: 61-65, 2011.

41. Nakata, J., Nakahari, A., Takahashi, C., Chikazawa, S., Hori, Y., Kanai, K., Ito, N., Higuchi, S., Hoshi, F.: Molecular cloning, expression in Escherichia coli, and development of monoclonal antibodies to feline cystatin C. Vet Immunol Immunopathol. 138: 231-234, 2010.

42. Kanai, K., Itoh, N., Yoshioka, K., Yonezawa, T., Ikadai, H., Hori, Y., Ito, Y., Nagai, N., Chikazawa, S., Hoshi, F., Higuchi, S.: Inhibitory effects of oral disulfiram on endotoxin-induced uveitis in rats. Curr Eye Res. 35: 892-899, 2010.

43. Hori, Y., Sano, N., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Acute volume load-related changes in plasma ANP and NT-proBNP concentrations in healthy dogs. Vet J. 185: 317–321, 2010.

44. Itoh, N., Kanai, K., Hori, Y., Hoshi, F., Higuchi, S.: Prevalence of Giardia intestinalis and other zoonotic intestinal parasites in private household dogs of the Hachinohe area in Aomori prefecture, Japan in 1997, 2002 and 2007. J Vet Sci. 10: 305-308, 2009.

45. Hori, Y., Kikuchi, M., Nakagawa, A., Yonezawa, T., Miura, H., Ohnami, Y.: Plasma atrial natriuretic peptide in healthy calves and calves with congenital heart disease. J Vet Int Med. 23: 653–656, 2009.

46. Hori, Y., Kunihiro, S., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: The relationship between invasive hemodynamic measurements and tissue Doppler-derived myocardial velocity and acceleration during isovolumic relaxation in healthy dogs. J Vet Med Sci. 71: 1419-1425, 2009.

47. Hori, Y., Kunihiro, S., Sato, S., Yoshioka, K., Hara, Y., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Doxycycline attenuates isoproterenol-induced myocardial fibrosis and matrix metalloproteinase activity in rats. Biol Pharm Bull. 32: 1678-1682, 2009.

48. Hori, Y., Ohshima, N., Kanai, K., Hoshi, F., Itoh, N., Higuchi, S.: Differences in the duration of diuretic effects and impact on the rennin-angiotensin-aldosterone system of furosemide in healthy dogs. J Vet Med Sci. 72: 13-18, 2010.

49. Okada, M., Kikuzuki, R., Harada, T., Hori, Y., Yamawaki, H., Hara, Y.: Captopril Attenuates Matrix Metalloproteinase-2 and -9 in Monocrotaline-Induced Right Ventricular Hypertrophy in Rats. J Pharmacol Sci. 108: 487-494, 2008.

50. Kanai, K., Fujisawa, A., Ikeguchi, M., Hori, Y., Shimamura, S., Nakao, R., Hoshi, F., Okano, S., Itoh, N., Higuchi, S.: A case of multiple uveal cysts associated with persistent pupillary membrane in dog. Anim. Eye Res. 27: 39-41, 2008.

51. Kanai, K., Hino, M., Hori, Y., Nakao, R., Hoshi, F., Itoh, N., Higuchi, S.: Circadian variations in salivary chromogranin a concentrations during a 24-hour period in dogs. J Vet Sci. 9: 423-425, 2008.

52. Hori, Y., Katou, A., Tsubaki, M., Kanai, K., Nakao, R., Hoshi, F., Itoh, N., Higuchi, S.: Assessment of diuretic effects and changes in plasma aldosterone concentration following oral administration of a single dose of furosemide or azosemide in healthy dogs. Am J Vet Res. 69: 1664-1669, 2008.

53. Hori, Y., Tsubaki, M., Katou, A., Ono, Y., Yonezawa, T., Li, X., Higuchi, SI.: Evaluation of NT-pro BNP and CT-ANP as markers of concentric hypertrophy in dogs with a model of compensated aortic stenosis. J Vet Int Med. 22; 1118-1123, 2008.

54. Itoh, N., Kanai, K., Hori, Y., Nakao, R., Hoshi, F., Higuchi, S.: Fenbendazole treatment of dogs with naturally acquired Strongyloides stercoralis infection. Vet Rec. 164: 559-560, 2009.

55. Hori, Y., Ukai, Y., Hoshi, F., Higuchi, S.: Volume loading-related changes in tissue Doppler images derived from the tricuspid valve annulus in dogs. Am J Vet Res. 69; 33-38, 2008.

56. Hori, Y., Yamano, S., Iwanaga, K., Kano, T., Tanabe, M., Uechi, M., Kanai, K., Nakao, R., Hoshi, F., Higuchi, S.: Evaluation of plasma C-terminal atrial natriuretic peptide in healthy cats and cats with heart disease. J Vet Int Med. 22: 135-139, 2008.

57. Uechi, M., Tanaka, Y., Aramaki, Y., Hori, Y., Ishikawa, Y., Ebisawa, T., Yamano, S.: Evaluation of the renin-angiotensin system in cardiac tissues of cats with pressure-overload cardiac hypertrophy. Am J Vet Res. 69: 343-348, 2008.

58. Hori, Y., Uechi, M., Ebisawa, T., Yamano, S., Yoshioka, K., Mutou, K.: The influence of gender on cardiac fibrosis induced by sympathetic stimulation. Chinese J Physiol. 51: 146-151, 2008.

59. Hori, Y., Ukai, Y., Uechi, M., Hoshi, F., Higuchi, S.: Relationships between velocities of pulmonary venous flow and plasma concentrations of atrial natriuretic peptide in healthy dogs. Am J Vet Res. 69: 465-470, 2008.

60. Hori, Y., Kanai, K., Nakao, R., Hoshi, F., Higuchi, S.: Assessing diastolic function with Doppler echocardiography using a novel index: Ratio of the transmitral early diastolic velocity to pulmonary diastolic velocity. J Vet Med Sci. 70: 359-366, 2008.

61. Hori, Y., Kano, T., Hoshi, F., Higuchi, S.: Relationship between tissue Doppler-derived RV systolic function and invasive hemodynamic measurements. Am J Physiol. 293: H120-125, 2007.

62. Hori, Y., Uechi, M., Indou, A., Yamano, S., Ebisawa, T., Teshima, K., Asano, K.: Changes in the myocardial performance index during dobutamine administration in anesthetized cats. Am J Vet Res. 68: 385-388, 2007.

63. Hori, Y., Sato, S., Hoshi, F., Higuchi, S.: Assessment of longitudinal tissue Doppler imaging of the left ventricular septum and free wall as an indicator of left ventricular systolic function in dogs. Am J Vet Res. 68: 1051-1057, 2007.

64. Hori, Y., Takusagawa, F., Ikadai, H., Uechi, M., Hoshi, F., Higuchi, S.: Effects of oral administration of furosemide and torsemide in healthy dogs. Am J Vet Res. 68: 1058-1063, 2007.

65. Hori, Y., Kunihiro, S., Hoshi, F., Higuchi, S.: Comparison of the myocardial performance index derived by use of pulsed Doppler echocardiography and tissue Doppler imaging in dogs with volume overload. Am J Vet Res. 68: 1177-1182, 2007.

66. Hori, Y., Uechi, M., Indou, A.: Effects of changes in loading conditions and heart rate on the myocardial performance index in cats. Am J Vet Res. 68: 1183-1187, 2007.

67. Ishikawa, Y., Uechi, M., Hori, Y., Ebisawa, T., Yamano, S., Enomoto, Y., Ugai, J.: Effects of enalapril in cats with pressure overload-induced left ventricular hypertrophy. J Feline Med Surg. 9: 29-35, 2007.

68. Ebisawa, T., Uechi, M., Hori, Y., Yamano, S.: Short term change of Urinary N-Acetyl-β-D-glucosaminidase in Reduced Kidney Mass with Renal Artery Ligation. J Vet Med Sci. 68: 1355-1357, 2006.

69. Hori, Y., Uechi, M., Kanakubo, K., Sano, T., Oyamada, T.: Canine ovarian serous papillary adenocarcinoma with neoplastic hypercalcemia. J Vet Med Sci. 68: 979-982, 2006.

70. Uechi, M., Hori, Y., Fujimoto, K., Ebisawa, T., Yamano, S., Maekawa, S.: Cardiovascular effects of a phosphodiesterase III inhibitor in the presence of carvedilol in dogs. J Vet Med Sci. 68: 549-553, 2006.